About the hSCRO

The Chancellor of the University of Pittsburgh has delegated authority, through the Vice Provost for Research Conduct and Compliance (designated Institutional Official), to the Human Stem Cell Research Oversight (hSCRO) Committee to initially and periodically review, approve, require modifications of or disapprove:
  • All human embryonic stem (hES) cell research being conducted by University faculty, staff, or students acting in their capacity as faculty, staff or students respectively, using University facilities and/or University resources
  • Limited categories of non-embryonic human stem cell research being conducted by University faculty, staff, or students acting in their capacity as faculty, staff, or students respectively, using University facilities and/or University resources

Frequently Asked Questions

Q: What types of human stem cell research requires review/approval by the hSCRO Committee?

  • hSCRO review/approval is required for ALL embryonic stem cell research and certain types of non-embryonic stem cell research, and is in addition to other required University research approvals, such as IACUC, IRB or IBC.

Q: What types of non-embryonic stem cell research is reviewed by the hSCRO?

  • A clinical trial (human subjects) where the administration of stem cells is considered to be experimental and not standard of care.
  • Transplantation of any type of human stem cell into an animal
  • Transplantation of cells that originated from human iPS cells or cells/cell lines that were derived from human embryonic cells (ES)

Q: Why does the hSCRO review non-embryonic stem cell research?

  • As there may be potential ethical concerns with any pluripotent stem cells research, the hSCRO Committee's purview includes oversight of both embryonice and certain types of non-embryonic stem cell research. The Committee's specialized expertise and knowledge of the broad scope of human stem cell research being conducted at the University of Pittsburgh allows the hSCRO Committee to serve as a valuable resource.

Q: How do I submit an application for review? How are hSCRO applications reviewed?

  • The investigator must complete an hSCRO application, and forward the application to hscro@pitt.edu for review. There are two levels of hSCRO review: Administrative Review by the hSCRO Chair (Registration) and hSCRO Committee Review. The type of review required depends upon the nature of the research described in the application. Researchers may refer to review descriptions in the hSCRO application or contact the office for assistance if needed.  See hSCRO Information page
page updated: 2 May 2017